Doctoral Student

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Doctoral candidate position available in Folkhälsan Research Center located in Meilahti, Helsinki.

Folkhälsan Research Center is an international research institute with two research programs: genetics and public health. Folkhälsan Research Center is a part of “Samfundet Folkhälsan i svenska Finland rf” and affiliated with the University of Helsinki, in Meilahti Campus area.

This position is available through funding by Jane and Aatos Erkko Foundation to Senior Scientist Shintaro Katayama, who works in close collaboration with Professor Juha Kere in the Folkhälsan Research Center in Helsinki, the Research Programs Unit at the University of Helsinki, and the Department of Biosciences and Nutrition at Karolinska Institutet. The focus of the research is aimed at understanding where and when RNAs are regulated in various human developmental stages [ref. *1] or the cell types [*2] to understand the disease [*3] or to use the deregulated RNAs for diagnosis [*4]. For the aim, the groups are willing also to develop new molecular and/or bioinformatics methods [*5, 6, 7].

Job description

As part of the joint research groups, there is a position available for a PhD candidate studying RNA (not DNA) editing in human normal epidermal cells and the model cells using high-throughput sequencing at Folkhälsan Research Center. The main duties will involve the establishment of a genome-scale analysis pipeline or tools to map the RNA editing sites in human cells using a nanopore sequencer as well as computational analysis of the experimental results. The analysis includes the integration of the other experimental results using other equipment or methods to investigate the association between gene expression and RNA editing. 

Qualification and experience

The successful candidates should have (or be close to completed) an MSc in Bioinformatics, Biostatistics, Systems Biology, Computational Biology or a related field. Experiences of an open-source software package development will be plus. Applicants interested in any of the above research areas will be considered.

Salary and contract

We will offer a salary according to the collective agreement for the Private Social Service Sector that will be based on previous qualifications, experience and performance in the position. A six-month trial period will be applied. The funds for this position are available for 24 months in the first instance.

Please send in your application via our electronic recruitment system latest Friday August 21 2020. Please include, in English, a brief cover letter motivating your interest and goals, a CV (2 pages, specifying your education and expertise in the topics listed above), and a list of possible previous publications. You may contact for questions. The selection processes will be conducted early September and the post is available immediately.

Selected publications:

*1 Töhönen, V. & Katayama, S. et al. Nat Commun 6, 8207 (2015).

*2 Hirabayashi, S. & Bhagat, S. et al. Nat Genet 51, 1369–1379 (2019).

*3 Katayama, S. & Panelius, J. et al. J. Invest. Dermatol. 139, 2058–2061.e4 (2019).

*4 Katayama, S. & Hammar, KS. et al. Eur. Respir. J. 55, 1901330 (2020).

*5 Katayama, S. et al. J. Bioinformatics 29, 2943–2945 (2013).

*6 Krjutškov, K. & Katayama, S. et al. Hum. Reprod. 31, 844–853 (2016).

*7 Katayama, S. et al. BMC Bioinformatics 20, 418–9 (2019).

Arbetsvillkor: Heltid
Publicerad: 07.07.2020
Ansök senast: 21.08.2020 23.59
Plats: Huvudstadsregionen, Nyland, Helsingfors
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